OAKLAND, Calif. -- Interceptions, batted pa ses and a mi sed open receiver in the end zone. looked rather ordinary for the first 26 minutes.That all changed with one short screen pa s to that turned into a spectacular touchdown and helped make the game a rout.Anderson's 51-yard catch-and-run started a run of five touchdown pa ses in five drives for Manning and the overcame a shaky start to hand the their 15th straight lo s, 41-17 on Sunday."Just a truly incredible effort play on his part to take a potentially catch for a lo s and turn it into a 50-something-yard touchdown," Manning said. "That really gave us a spark."Manning threw a pair of early interceptions that put Denver (7-2) in a hole against the NFL's only winle s team. Anderson got them out Freddy Galvis Jersey of it when he broke three tackles and weaved through the entire Oakland defense on his touchdown late in the first half."It easily could have been maybe a catch for minus-2 yards," Manning said. "Next thing you know he breaks a tackle and I don't know how many guys he made mi s."Manning added two TD pa ses to and two more to as the rebounded from last week's lo s at New England by beating up on the (0-9).Manning threw for 340 yards and extended his Brad Hand Jersey record with at least two touchdown pa ses to 15 straight games."All week we had a bad taste in our mouths because that game was definitely embarra sing," Sanders said. "It was something that we don't want to go through again, obviously, in the rest of the season."Anderson, who grew up in nearby Vallejo and attended college at California, finished with 90 yards rushing and 73 receiving. had 11 catches for 108 yards.There was almost nothing positive from the in their first blowout lo s since interim coach replaced the fired after four games. threw for 192 yards on 47 attempts, most of the production coming on a meaningle s touchdown drive in the closing minutes. He also had two interceptions. The running game was limited to 30 yards on 15 carries and the defense was completely overmatched after a spirited start."They're looking for the gold at the end of the rainbow and it hasn't been there," Sparano said. "We have to stay the course and believe in the things that we're doing and we're getting better as a football team. I know this is not an indicator of that."The game - and season - could be summed up in one play for Oakland early in the third Kirby Yates Jersey quarter. Carr was under pre sure when he dumped off a pa s to offensive lineman . Barnes looked shocked when he caught the ball, but ran with it despite an ineligible receiver. knocked the ball loose and Jr. recovered at the 18.That set up a 10-yard touchdown pa s to Johnny Manziel Jersey that put the up 28-10 and in control.Manning struggled early, throwing an interception on the second play from scrimmage to DJ Hayden. That set up a 41-yard field goal by that gave the their first lead against the since Tim Tebow was the Denver quarterback in 2011.The then got field goals on a pair of drives inside the Oakland 20 as Manning struggled to get into rhythm. The problems for Manning got worse when defensive end made an athletic interception, jumping to tip a pa s and then catching it himself to give Oakland the ball at the 12. Carr capitalized with a 5-yard pa s to that put the up 10-6.The game quickly changed after Carr was intercepted by on a poor pa s over the middle.On third-and-8, Manning threw a short pa s to Anderson, who immediately broke a tackle from . He then ran attempts by and on his way to the end zone."There seems to be a play every game that happens to us and then everything kind of snowballs from there," Woodson said. "There were a couple mi sed tackles, mine included, which I feel like, man, 'I'm part of the play that really turned the game around.' That's one I'll be thinking about all night."After a three-and-out by Oakland, Manning added a 32-yard touchdown pa s to Sanders that put Denver up 20-10 at the half.NOTES: tied Randy Mo s (2007) and three others for most touchdown catches through nine games with 12. He is the first tight end in NFL history with back- Manuel Margot Jersey to-back 12-touchdown seasons. ... Hayden (groin) and RT (head) left the game with injuries.Copyright 2014 by The A sociated Pre sRelive 's performance against the with