Fibroid disease symptoms can vary widely depending on the size, number, and location of uterine fibroids. Many people with fibroids may not notice any symptoms at first, while others experience discomfort that affects daily life. Common signs include heavy or prolonged menstrual bleeding, pelvic pressure or pain, bloating, and lower back discomfort. Some may also notice frequent urination or constipation caused by fibroids pressing on nearby organs.